Interference of potential pre-analytical confounders on co-oximetry and electrolyte concentrations were studied. Obtained data were compared against preset quality specifications. Based on the CLSI EP9-A2 evaluation protocol, a method comparison with the Siemens RapidPoint 500 and Abbott i-STAT CG8+ was performed. The estimated total error was calculated based on the mean of the range claimed by the manufacturer. Total imprecision was estimated according to the CLSI EP5-A2 protocol. We evaluated the (pre-)analytical performance of a novel cartridge-type blood gas analyzer, the GEM Premier 5000 (Werfen), for the determination of pH, partial carbon dioxide pressure (pCO 2 ), partial oxygen pressure (pO 2 ), sodium (Na + ), potassium (K + ), chloride (Cl - ), ionized calcium ( i Ca 2+ ), glucose, lactate, and total hemoglobin (tHb). Point-of-care blood gas test results may benefit therapeutic decision making by their immediate impact on patient care. Oyaert, Matthijs Van Maerken, Tom Bridts, Silke Van Loon, Silvi Laverge, Heleen Stove, Veronique The need for point-of-care medical diagnostic tools is evident, particularly in low-resource and rural settings, and a full.Īnalytical and pre-analytical performance characteristics of a novel cartridge-type blood gas analyzer for point-of-care and laboratory testing. N Engl J Med 380(22):2146–2155.Microfluidic cartridges for automated, point-of-care blood cell countingįull Text Available Disposable, low-cost microfluidic cartridges for automated blood cell counting applications are presented in this article. Mehran R, Dangas GD, Weisbord SD (2019) Contrast-associated acute kidney injury. Īndreucci M, Faga T, Pisani A, Sabbatini M, Michael A (2014) Acute kidney injury by radiographic contrast media: pathogenesis and prevention. Weisbord SD, Du Cheryon D (2018) Contrast-associated acute kidney injury is a myth: no. Van der Molen AJ, Reimer P, Dekkers IA, Bongartz G, Bellin M-F, Bertolotto M, Clement O, Heinz-Peer G, Stacul F, Webb JAW, Thomsen HS (2018) Post-contrast acute kidney injury – part 1: definition, clinical features, incidence, role of contrast medium and risk factors. They seem to be a good screening tool however, any low eGFR values should be further examined.Ĭontrast-enhanced imaging Contrast-induced kidney injury Creatinine Diagnostic imaging Estimated glomerular filtration rate Point-of-care testing.ĭavenport MS, Perazella MA, Yee J, Dillman JR et al (2020) Use of intravenous iodinated contrast media in patients with kidney disease: consensus statements from the American college of radiology and the national kidney foundation. POC devices are moderately accurate at detecting renal impairment in patients undergoing radiological investigations. The POC devices did not miss any high-risk patients but underreported eGFR values in certain patients. iSTAT had a R 2 value of 0.83 and coefficient variation of 7.36%. Statistical analysis revealed that the StatSensor R 2 value was 0.77, and coefficient variation was 10.65%. One hundred one patients underwent the Abbott iSTAT analysis, 139 patients underwent Nova StatSensor analysis, and 53 had both. One hundred eighty-six patients were included in the study. eGFR values were stratified as high risk (eGFR < 30), moderate risk (eGFR 30-59) and low risk (eGFR ≥ 60).
Renal function was calculated using eGFR via the CKD-EPI result. The two values were analysed and compared.
Patients undergoing routine radiological investigations had blood collected and analysed by a POC method and the laboratory method (Beckman AU5800). Two POC devices were evaluated, the Nova StatSensor and Abbott iSTAT. Point of care (POC) devices offer a quick estimation of renal function, potentially improving workflows in radiology departments. One of the biggest risk factors for developing PC-AKI is the presence of pre-existing renal dysfunction, making it important to measure the renal function prior to contrast administration. There exists a small risk of post-contrast acute kidney injury in patients receiving IV contrast. Intravenous iodinated contrast is a commonly used diagnostic aid to improve image quality on computed tomography.
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